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Proceedings Paper

Optimization of an impedance sensor for droplet-based microfluidic systems
Author(s): Brian P. Cahill
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Paper Abstract

Digital microfluidics utilises discrete droplets to increase the throughput of chemical and biological assays. There is a great need for sensing techniques that can help automate droplet handing. This work aims to illustrate by means of finite element modelling the factors that affect the measurement of droplet impedance in a thin-walled glass capillary. These include modelling the effect of varying capillary wall thickness, electrode spacing, electrode area, droplet size, shielding and droplet conductivity. The simulation is performed using COMSOL finite element analysis software. The model serves to aid the optimization of the measurement system for application in the measurement of the presence/absence of droplets as well as their chemical and biological content.

Paper Details

Date Published: 5 May 2011
PDF: 8 pages
Proc. SPIE 8066, Smart Sensors, Actuators, and MEMS V, 80660F (5 May 2011); doi: 10.1117/12.886887
Show Author Affiliations
Brian P. Cahill, Institute for Bioprocessing and Analytical Measurement Techniques (Germany)

Published in SPIE Proceedings Vol. 8066:
Smart Sensors, Actuators, and MEMS V
Ulrich Schmid; José Luis Sánchez-Rojas; Monika Leester-Schaedel, Editor(s)

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