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Proceedings Paper

Impedance spectroscopy on a digital microfluidic platform
Author(s): Thomas Lederer; Stefan Clara; Bernhard Jakoby; Wolfgang Hilber
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Paper Abstract

Digital microfluidics combines the advantages of low consumption of reagents with a high flexibility of processing fluid samples automatically. For applications in life sciences not only the processing but also the characterization of fluid analytes is crucial. In this contribution a microfluidic platform combining the actuation principle of electro wetting on dielectrics for droplet manipulations and the sensor principle of impedance spectroscopy for the characterization of fluid composition and condition is presented. The fabrication process of the microfluidic platform comprises physical vapor deposition and structuring of the metal electrodes onto a substrate, the deposition of a dielectric isolator and a hydrophobic top coating. The key advantage of this microfluidic chip is the common electric nature of the sensor and the actuation principle, so no additional sensor integration is necessary. Multiple measurements on fluids of different composition (including rigid particles and biologic cells) and of different conditions (temperature, sedimentation) were performed as well as online monitoring of in process parameters changing over time. These sample applications demonstrate the versatile applications of this combined technology.

Paper Details

Date Published: 5 May 2011
PDF: 12 pages
Proc. SPIE 8066, Smart Sensors, Actuators, and MEMS V, 806625 (5 May 2011); doi: 10.1117/12.886773
Show Author Affiliations
Thomas Lederer, Johannes Kepler Univ. Linz (Austria)
Stefan Clara, Johannes Kepler Univ. Linz (Austria)
Bernhard Jakoby, Johannes Kepler Univ. Linz (Austria)
Wolfgang Hilber, Johannes Kepler Univ. Linz (Austria)

Published in SPIE Proceedings Vol. 8066:
Smart Sensors, Actuators, and MEMS V
Ulrich Schmid; José Luis Sánchez-Rojas; Monika Leester-Schaedel, Editor(s)

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