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Proceedings Paper

Development of a near-infrared spectroscopic system for monitoring urine glucose level for the use of long-term home healthcare
Author(s): Shinobu Tanaka; Yuuto Hayakawa; Mitsuhiro Ogawa; Ken-ichi Yamakoshi
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Paper Abstract

We have been developing a new technique for measuring urine glucose concentration using near infrared spectroscopy (NIRS) in conjunction with the Partial Least Square (PLS) method. In the previous study, we reported some results of preliminary experiments for assessing feasibility of this method using a FT-IR spectrometer. In this study, considering practicability of the system, a flow-through cell with the optical path length of 10 mm was newly introduced. Accuracy of the system was verified by the preliminary experiments using urine samples. From the results obtained, it was clearly demonstrated that the present method had a capability of predicting individual urine glucose level with reasonable accuracy (the minimum value of standard error of prediction: SEP = 22.3 mg/dl) and appeared to be a useful means for long-term home health care. However, mean value of SEP obtained by the urine samples from ten subjects was not satisfactorily low (53.7 mg/dl). For improving the accuracy, (1) mechanical stability of the optical system should be improved, (2) the method for normalizing the spectrum should be reconsidered, and (3) the number of subject should be increased.

Paper Details

Date Published: 28 December 2010
PDF: 6 pages
Proc. SPIE 7544, Sixth International Symposium on Precision Engineering Measurements and Instrumentation, 75441D (28 December 2010); doi: 10.1117/12.886007
Show Author Affiliations
Shinobu Tanaka, Kanazawa Univ. (Japan)
Yuuto Hayakawa, Kanazawa Univ. (Japan)
Mitsuhiro Ogawa, Kanazawa Univ. (Japan)
Ken-ichi Yamakoshi, Kanazawa Univ. (Japan)

Published in SPIE Proceedings Vol. 7544:
Sixth International Symposium on Precision Engineering Measurements and Instrumentation
Jiubin Tan; Xianfang Wen, Editor(s)

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