
Proceedings Paper
Shape-guided complex-source fluorescence tomographyFormat | Member Price | Non-Member Price |
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Paper Abstract
Local fine representation of the fluorescence map on the standard mesh can be redundant in the sense that the
reconstruction resolution is usually limited in such a severely ill-posed problem. Using global characteristic shape
functions that can approximately capture the major structural information, we study fluorescence tomography with a new
shape-guided representation based on some underlying mesh. Moreover, the proposed method can naturally enforce the
prior coexistence of fluorescence yield and lifetime when fluorescence maps are formulated in complex sources. The
simulation results suggest that, compared with standard pixel-wise representation, the shape-guided representation offers
better localization of inclusions with improved quantitative accuracy, particularly in the case with inclusions of low
fluorescence contrast, such as 2:1 inclusion-to-background ratio, and is more robust to the initial guess and the noise.
Paper Details
Date Published: 1 March 2011
PDF: 10 pages
Proc. SPIE 7896, Optical Tomography and Spectroscopy of Tissue IX, 78960Y (1 March 2011); doi: 10.1117/12.885008
Published in SPIE Proceedings Vol. 7896:
Optical Tomography and Spectroscopy of Tissue IX
Bruce Jason Tromberg; Arjun G. Yodh; Mamoru Tamura; Eva Marie Sevick-Muraca; Robert R. Alfano, Editor(s)
PDF: 10 pages
Proc. SPIE 7896, Optical Tomography and Spectroscopy of Tissue IX, 78960Y (1 March 2011); doi: 10.1117/12.885008
Show Author Affiliations
Yuting Lin, Univ. of California, Irvine (United States)
Hao Gao, Univ. of California, Los Angeles (United States)
Hao Gao, Univ. of California, Los Angeles (United States)
Gultekin Gulsen, Univ. of California, Irvine (United States)
Published in SPIE Proceedings Vol. 7896:
Optical Tomography and Spectroscopy of Tissue IX
Bruce Jason Tromberg; Arjun G. Yodh; Mamoru Tamura; Eva Marie Sevick-Muraca; Robert R. Alfano, Editor(s)
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