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Proceedings Paper • Open Access

Functionalized DNA materials for sensing and medical applications
Author(s): Dwight L. Woolard; James O. Jensen

Paper Abstract

The U.S. Army has strong interests in nanoscale architectures that enable enhanced extraction and controllable multiplication of the THz/IR regime spectral signatures associated with specific bio-molecular targets. Emerging DNAbased nano-assemblies (i.e., either materials or structural devices) will be discussed that realize novel sensing paradigms through the incorporation of organic and/or biological molecules such that they effect highly predictable and controllable changes into the electro-optical properties of the resulting superstructures. Results will be given to illustrate the utility of functionalized DNA materials in biological (and chemical) sensing, and to demonstrate how the basic science can be leveraged to study and develop synthetic antibodies, reporters and vaccines for future medical applications.

Paper Details

Date Published: 13 May 2011
PDF: 13 pages
Proc. SPIE 8031, Micro- and Nanotechnology Sensors, Systems, and Applications III, 80310V (13 May 2011); doi: 10.1117/12.884538
Show Author Affiliations
Dwight L. Woolard, U.S. Army Research Office (United States)
James O. Jensen, U.S. Army Edgewood Chemical Biological Ctr. (United States)

Published in SPIE Proceedings Vol. 8031:
Micro- and Nanotechnology Sensors, Systems, and Applications III
Thomas George; M. Saif Islam; Achyut K. Dutta, Editor(s)

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