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Proceedings Paper

A hybrid approach combining microCT and fluorescence tomography: imaging workflow and system of coordinate registration
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Paper Abstract

A fluorescence imaging system was designed to interface with a microCT device. We focus on refining the workflow for meshing and the coordinate registration of the two systems. The former is performed by projection imaging in the microCT, reconstructing a volume, segmenting using image processing software, and meshing using the NIRFAST software. The coordinate registration is performed by exploiting the geometry of the fluorescence system. We determine the location of the geometrical center of a subject, which can be used to derive a translation between instruments. The co-registration is validated by imaging optical phantoms.

Paper Details

Date Published: 10 February 2011
PDF: 8 pages
Proc. SPIE 7892, Multimodal Biomedical Imaging VI, 789213 (10 February 2011); doi: 10.1117/12.881449
Show Author Affiliations
Robert Holt, Dartmouth College (United States)
Fadi El-Ghussein, Dartmouth College (United States)
Kenneth M. Tichauer, Dartmouth College (United States)
Frederic Leblond, Dartmouth College (United States)
Brian W. Pogue, Dartmouth College (United States)


Published in SPIE Proceedings Vol. 7892:
Multimodal Biomedical Imaging VI
Fred S. Azar; Xavier Intes, Editor(s)

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