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Proceedings Paper

Forward model of Cerenkov luminescence tomography with the third-order simplified spherical harmonics approximation
Author(s): Jianghong Zhong; Jie Tian; Xin Yang; Chenghu Qin
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Paper Abstract

Applying Cerenkov luminescence tomography (CLT) to localizing Cerenkov light sources in situ is still in its nascent stage. One of the obstacles hindering the development of the CLT is the lack of dedicated imaging mode. In this contribution, the paper presented a Cerenkov optical imaging mode, in which the propagation of optical photons inside tissues generated by the Vavilov-Cerenkov effect is modeled based on simplified spherical harmonics approximation. As a significantly more transport-like and computational-efficient approximation theory, the performance of the third-order simplified spherical harmonics approximation (SP3) in the CLT forward is investigated in stages. Finally, the performance of the proposed forward model is validated using numerical phantoms and compared with the simulation data based on the Monte Carlo method.

Paper Details

Date Published: 16 March 2011
PDF: 6 pages
Proc. SPIE 7961, Medical Imaging 2011: Physics of Medical Imaging, 796120 (16 March 2011); doi: 10.1117/12.878003
Show Author Affiliations
Jianghong Zhong, Institute of Automation (China)
Jie Tian, Institute of Automation (China)
Xin Yang, Institute of Automation (China)
Chenghu Qin, Institute of Automation (China)

Published in SPIE Proceedings Vol. 7961:
Medical Imaging 2011: Physics of Medical Imaging
Norbert J. Pelc; Ehsan Samei; Robert M. Nishikawa, Editor(s)

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