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Proceedings Paper

Effect of de-noising and DDRV correction on cone-beam SPECT reconstruction with non-uniform attenuation
Author(s): Hao Zhang; Junhai Wen; Wen Yin; Cuifen Li; Kangping Zhang; Zhengrong Liang
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Paper Abstract

SPECT (single photon emission computed tomography) is a non-invasive, cost-effective means for assessment of tissue/organ functions in nuclear medicine. For more accurate diagnosis, quantitative reconstruction of radiotracer concentration at any location inside the body is desired. To achieve this goal, we have to address a number of factors that significantly degrade the acquired projection data. The cone-beam SPECT system has higher resolution comparing with parallel-beam and fan-beam SPECT, which is highly advantageous in small object detection. In this paper, we used four analytical reconstruction schemes for cone-beam SPECT that allow simultaneous compensation for non-uniform attenuation and distance-dependent resolution variation (DDRV), as well as accurate treatment of Poisson noise. The simulation results show that the reconstruction scheme 1 and 4 both can obtain good reconstruction results.

Paper Details

Date Published: 16 March 2011
PDF: 8 pages
Proc. SPIE 7961, Medical Imaging 2011: Physics of Medical Imaging, 796142 (16 March 2011); doi: 10.1117/12.877352
Show Author Affiliations
Hao Zhang, Beijing Institute of Technology (China)
Junhai Wen, Beijing Institute of Technology (China)
Wen Yin, Beijing Univ. of Technology (China)
Cuifen Li, Beijing Institute of Technology (China)
Kangping Zhang, Beijing Institute of Technology (China)
Zhengrong Liang, Stony Brook Univ. (United States)

Published in SPIE Proceedings Vol. 7961:
Medical Imaging 2011: Physics of Medical Imaging
Norbert J. Pelc; Ehsan Samei; Robert M. Nishikawa, Editor(s)

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