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Proceedings Paper

Development of a hand-held 3D photoacoustic imaging system for breast cancer detection
Author(s): Hazem Al-Aabed; Michael Roumeliotis; Jeffrey J. L. Carson
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Paper Abstract

Photoacoustic (PA) imaging is a non-invasive imaging modality that employs non-ionizing near infrared (NIR) laser light to obtain optical images of tissues with depth penetration and resolution comparable to ultrasound imaging. PA images are created by illuminating tissues with a short laser pulse (~10 ns), which causes optically absorbing structures to heat up slightly, but so rapidly that conditions of thermal and stress confinement are met and the structure emits a pressure wave at ultrasonic frequencies. Detection of the pressure waves at the tissue surface with an ultrasound transducer array provides the data needed to reconstruct the distribution of light-absorbing structures within the tissue. Since it is recognized that cancerous breast lesions absorb light to a greater degree than surrounding normal tissue, PA imaging is a viable candidate for detection of lesions within the intact human breast. Therefore, we have constructed a transportable PA imaging system suitable for breast imaging. The system incorporates a hand-held transducer array with 30 detector elements arranged on a ring. Laser light is delivered coaxially in relation to the ring using a fiber optic light guide. The supporting hardware includes a NIR tuneable laser, transducer cabling, 30 preamplifiers, 30 independent data acquisition channels with onboard memory, and a computer with control and image reconstruction software. Initial tests with the transducer array suggest that it has sufficient sensitivity to detect optically absorbent objects on the order of 1- mm at a depth of 2 cm. It is anticipated that a small hand-held PA imaging unit will be amenable to patient work-up and would complement standard ultrasound imaging.

Paper Details

Date Published: 22 September 2010
PDF: 6 pages
Proc. SPIE 7750, Photonics North 2010, 77501X (22 September 2010); doi: 10.1117/12.877258
Show Author Affiliations
Hazem Al-Aabed, Lawson Health Research Institute (Canada)
The Univ. of Western Ontario (Canada)
Michael Roumeliotis, Lawson Health Research Institute (Canada)
The Univ. of Western Ontario (Canada)
Jeffrey J. L. Carson, Lawson Health Research Institute (Canada)
The Univ. of Western Ontario (Canada)

Published in SPIE Proceedings Vol. 7750:
Photonics North 2010
Henry P. Schriemer; Rafael N. Kleiman, Editor(s)

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