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Proceedings Paper

Hybrid CAD scheme for lung nodule detection in PET/CT images
Author(s): Atsushi Teramoto; Hiroshi Fujita; Yoya Tomita; Katsuaki Takahashi; Osamu Yamamuro; Tsuneo Tamaki; Naoki Hayashi; Shinichi Tamai; Masami Nishio; Wei-Ping Chen; Toshiki Kobayashi
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Paper Abstract

Lung cancer is the leading cause of death among male in the world. PET/CT is useful for the detection of early lung cancer since it is an imaging technique that has functional and anatomical information. However, radiologist has to examine using the large number of images. Therefore reduction of radiologist's load is strongly desired. In this study, hybrid CAD scheme has been proposed to detect lung nodule in PET/CT images. Proposed method detects the lung nodule from both CT and PET images. As for the detection in CT images, solitary nodules are detected using Cylindrical Filter that we developed. PET images are binarized based on standard uptake value (SUV); highly uptake regions are detected. FP reduction is performed using seven characteristic features and Support Vector Machine. Finally by integrating these results, candidate regions are obtained. In the experiment, we evaluated proposed method using 50 cases of PET/CT images obtained for the cancer-screening program. We evaluated true-positive fraction (TPF) and the number of false positives / case (FPs/case). As a result, TPFs for CT and PET were 0.67 and 0.38, respectively. By integrating the both results, TPF was improved to 0.80. These results indicate that our method may be useful for the lung cancer detection using PET/CT images.

Paper Details

Date Published: 9 March 2011
PDF: 6 pages
Proc. SPIE 7963, Medical Imaging 2011: Computer-Aided Diagnosis, 796335 (9 March 2011); doi: 10.1117/12.877104
Show Author Affiliations
Atsushi Teramoto, Fujita Health Univ. (Japan)
Hiroshi Fujita, Gifu Univ. (Japan)
Yoya Tomita, East Nagoya Imaging Diagnosis Ctr. (Japan)
Katsuaki Takahashi, East Nagoya Imaging Diagnosis Ctr. (Japan)
Osamu Yamamuro, East Nagoya Imaging Diagnosis Ctr. (Japan)
Tsuneo Tamaki, East Nagoya Imaging Diagnosis Ctr. (Japan)
Naoki Hayashi, Fujita Health Univ. (Japan)
Shinichi Tamai, Nagoya Radiological Diagnosis Ctr. (Japan)
Masami Nishio, Nagoya Radiological Diagnosis Ctr. (Japan)
Wei-Ping Chen, East Nagoya Imaging Diagnosis Ctr. (Japan)
Toshiki Kobayashi, Nagoya Radiological Diagnosis Ctr. (Japan)

Published in SPIE Proceedings Vol. 7963:
Medical Imaging 2011: Computer-Aided Diagnosis
Ronald M. Summers M.D.; Bram van Ginneken, Editor(s)

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