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Proceedings Paper

Feasibility of detecting mineral content in turbid medium using stimulated Raman photoacoustic imaging
Author(s): Rajan Arora; Georgi I. Petrov; Hao F. Zhang; Vladislav V. Yakovlev
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Paper Abstract

Osteoporosis is a bone disease that leads to the increasing risk of bone fracture. It is associated with a reduced mineral content, which results in the change of the bone architecture. Raman spectroscopy has an intrinsic sensitivity to the chemical content of the bone, but its application to study bones in vivo is limited due to strong optical scattering in tissue. It is proposed that Raman excitation with photoacoustic detection can successfully address the problem of chemically specific imaging in deep tissue. In this report, the principal possibility of such approach is evaluated.

Paper Details

Date Published: 21 February 2011
PDF: 7 pages
Proc. SPIE 7892, Multimodal Biomedical Imaging VI, 78920N (21 February 2011); doi: 10.1117/12.875442
Show Author Affiliations
Rajan Arora, Univ. of Wisconsin-Milwaukee (United States)
Georgi I. Petrov, Univ. of Wisconsin-Milwaukee (United States)
Hao F. Zhang, Northwestern Univ. (United States)
Vladislav V. Yakovlev, Univ. of Wisconsin-Milwaukee (United States)

Published in SPIE Proceedings Vol. 7892:
Multimodal Biomedical Imaging VI
Fred S. Azar; Xavier Intes, Editor(s)

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