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Proceedings Paper

Differentiating retroperitoneal liposarcoma tumors with optical coherence tomography
Author(s): Dina Lev; Stepan A. Baranov; Esteban F. Carbajal; Eric D. Young; Raphael E. Pollock; Kirill V. Larin
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Paper Abstract

Liposarcoma (LS) is a rare and heterogeneous group of malignant mesenchymal neoplasms exhibiting characteristics of adipocytic differentiation. Currently, radical surgical resection represents the most effective and widely used therapy for patients with abdominal/retroperitoneal LS, but the presence of contiguous essential organs, such as the kidney, pancreas, spleen, adrenal glands, esophagus or colon, as well as often reoccurrence of LS in A/RP calls for the enhancement of surgical techniques to minimize resection and avoid LS reoccurrences. Difficulty in detecting the margins of neoplasms due to their affinity to healthy fat tissue accounts for the high reoccurrence of LS within A/RP. Nowadays, the microscopic detection of margins is possible only by use of biopsy, and the minimization of surgical resection of healthy tissues is challenging. In this presentation we'll demonstrate the initial OCT results for the imaging and distinction of LS and normal human fat tissues and clear detection of tumor boundaries.

Paper Details

Date Published: 21 February 2011
PDF: 5 pages
Proc. SPIE 7890, Advanced Biomedical and Clinical Diagnostic Systems IX, 78900U (21 February 2011); doi: 10.1117/12.875085
Show Author Affiliations
Dina Lev, The Univ. of Texas M.D. Anderson Cancer Ctr. (United States)
Stepan A. Baranov, Univ. of Houston (United States)
Esteban F. Carbajal, Univ. of Houston (United States)
Eric D. Young, The Univ. of Texas M.D. Anderson Cancer Ctr. (United States)
Raphael E. Pollock, The Univ. of Texas M.D. Anderson Cancer Ctr. (United States)
Kirill V. Larin, Univ. of Houston (United States)
Baylor College of Medicine (United States)
Saratov State Univ. (Russian Federation)

Published in SPIE Proceedings Vol. 7890:
Advanced Biomedical and Clinical Diagnostic Systems IX
Anita Mahadevan-Jansen; Tuan Vo-Dinh; Warren S. Grundfest M.D., Editor(s)

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