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Proceedings Paper

Automated stent strut coverage and apposition analysis of in-vivo intra coronary optical coherence tomography images
Author(s): Giovanni J. Ughi; Tom Adriaenssens; Kevin Onsea; Peter Kayaert; Christophe Dubois; Mark Coosemans; Peter Sinnaeve; Walter Desmet; Jan D'hooge
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Paper Abstract

Several studies have proven that intra-vascular OCT is an appropriate imaging modality able to evaluate stent strut apposition and coverage in coronary arteries. Currently image processing is performed manually resulting in a very time consuming and labor intensive procedure. We propose an algorithm for fully automatic individual stent strut apposition and coverage analysis in coronary arteries. The vessel lumen and stent strut are automatically detected and segmented through analysis of the intensity profiles of the A-scan lines. From these data, apposition and coverage can then be estimated automatically. The algorithm was validated using manual measurement (performed by two trained cardiologists) as a reference. 108 images were taken at random from in-vivo pullbacks from 9 different patient presenting 'real-life' situations (i.e. blood residual, small luminal objects and artifacts). High Pearson's correlation coefficients were found (R = 0.96 - 0.95) between the automated and manual measurements while Bland-Altman statistics showed no significant bias with good limits of agreement. As such, it was shown that the presented algorithm provides a robust and a fast tool to automatically estimate apposition and coverage of stent struts in in-vivo pullbacks. This will be important for the integration of this technology in clinical routine and large clinical trials.

Paper Details

Date Published: 11 February 2011
PDF: 9 pages
Proc. SPIE 7889, Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XV, 78890O (11 February 2011); doi: 10.1117/12.874612
Show Author Affiliations
Giovanni J. Ughi, Catholic Univ. Leuven (Belgium)
Tom Adriaenssens, Univ. Hospitals Leuven (Belgium)
Kevin Onsea, Univ. Hospitals Leuven (Belgium)
Peter Kayaert, Univ. Hospitals Leuven (Belgium)
Christophe Dubois, Catholic Univ. Leuven (Belgium)
Univ. Hospitals Leuven (Belgium)
Mark Coosemans, Univ. Hospitals Leuven (Belgium)
Peter Sinnaeve, Catholic Univ. Leuven (Belgium)
Univ. Hospitals Leuven (Belgium)
Walter Desmet, Catholic Univ. Leuven (Belgium)
Univ. Hospitals Leuven (Belgium)
Jan D'hooge, Catholic Univ. Leuven (Belgium)

Published in SPIE Proceedings Vol. 7889:
Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XV
James G. Fujimoto; Joseph A. Izatt; Valery V. Tuchin, Editor(s)

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