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Proceedings Paper

Determining size, shape, and orientation of non-spherical scatterers using the fiber optic interferometric two-dimensional scattering (FITS) system
Author(s): Michael Giacomelli; Yizheng Zhu; John Lee; Adam Wax
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Paper Abstract

Angle-resolved scattering measurements have shown promise as a method of detecting neoplasia and analyzing cellular structure. Recently we have developed new systems for interferometric measurement of two-dimensional, depth resolved scattered fields with excellent depth resolution and polarization sensitivity. We present inverse analysis of oriented ensembles of micro-spheroidal phantoms and cells showing sub-wavelength accuracy in size and shape determination, and additionally precise estimates of scatterer orientation. Finally we show that inverse fits provided are essentially free of multiple solutions over a wide range of possible scatterer sizes and shapes.

Paper Details

Date Published: 11 February 2011
PDF: 6 pages
Proc. SPIE 7907, Biomedical Applications of Light Scattering V, 790711 (11 February 2011); doi: 10.1117/12.874081
Show Author Affiliations
Michael Giacomelli, Duke Univ. (United States)
Yizheng Zhu, Duke Univ. (United States)
John Lee, Duke Univ. (United States)
Adam Wax, Duke Univ. (United States)

Published in SPIE Proceedings Vol. 7907:
Biomedical Applications of Light Scattering V
Adam P. Wax; Vadim Backman, Editor(s)

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