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Proceedings Paper

Ablative efficiency of lithium triborate laser vaporization and conventional transurethral resection of the prostate: a comparison using transrectal three-dimensional ultrasound volumetry
Author(s): Oliver Gross; Tullio Sulser; Lukas J. Hefermehl; Daniel D. Strebel; Remo Largo; Ashkan Mortezavi; Cédric Poyet; Daniel Eberli; Matthias Zimmermann; Alexander Müller; Maurice S. Michel; Michael Müntener; Hans-Helge Seifert; Thomas Hermanns
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Paper Abstract

Introduction and objectives: It is unknown if tissue ablation following 120W lithium triborate (LBO) laser vaporization (LV) of the prostate is comparable to that following transurethral resection of the prostate (TURP). Therefore, transrectal 3D-ultrasound volumetry of the prostate was performed to compare the efficiency of tissue ablation between LBO-LV and TURP. Methods: Between 03/2008 and 03/2010 110 patients underwent routine LBO-LV (n=61) or TURP (n=49). Transrectal 3D-ultrasound with planimetric volumetry of the prostate was performed pre-operatively, after catheter removal, 6 weeks and 6 months. Results: Median prostate volume was 52.5ml in the LV group and 46.9ml in the TURP group. After catheter removal, median absolute volume reduction (LV: 7.05ml, TURP: 15.8ml) and relative volume reduction (15.9% vs. 34.2%) were significantly lower in the LV group (p<0.001). After 6 weeks/ 6 months, the relative volume reduction but not the absolute remained significantly lower in the LV group. Conclusions: LBO-LV is an efficient procedure evidenced by an absolute tissue ablation not significantly different to that after TURP. However, TURP seems to be superior due to a higher relative tissue ablation. The differences in tissue ablation had no impact on the early clinical outcome. Delayed volume reduction indicates that prostatic swelling occurs early after LV and then decreases subsequently.

Paper Details

Date Published: 17 February 2011
PDF: 8 pages
Proc. SPIE 7883, Photonic Therapeutics and Diagnostics VII, 78831I (17 February 2011); doi: 10.1117/12.874024
Show Author Affiliations
Oliver Gross, Univ. Hospital Zürich (Switzerland)
Tullio Sulser, Univ. Hospital Zürich (Switzerland)
Lukas J. Hefermehl, Univ. Hospital Zürich (Switzerland)
Daniel D. Strebel, Univ. Hospital Zürich (Switzerland)
Remo Largo, Univ. Hospital Zürich (Switzerland)
Ashkan Mortezavi, Univ. Hospital Zürich (Switzerland)
Cédric Poyet, Univ. Hospital Zürich (Switzerland)
Daniel Eberli, Univ. Hospital Zürich (Switzerland)
Matthias Zimmermann, Univ. Hospital Zürich (Switzerland)
Alexander Müller, Univ. Hospital Zürich (Switzerland)
Maurice S. Michel, Univ. Hospital Zürich (Switzerland)
Univ. of Heidelberg (Germany)
Michael Müntener, Univ. Hospital Zürich (Switzerland)
Hans-Helge Seifert, Univ. Hospital Zürich (Switzerland)
Thomas Hermanns, Univ. Hospital Zürich (Switzerland)

Published in SPIE Proceedings Vol. 7883:
Photonic Therapeutics and Diagnostics VII
Kenton W. Gregory M.D.; Nikiforos Kollias; Andreas Mandelis; Henry Hirschberg M.D.; Hyun Wook Kang; Anita Mahadevan-Jansen; Brian Jet-Fei Wong M.D.; Justus F. R. Ilgner M.D.; Bodo E. Knudsen M.D.; E. Duco Jansen; Steen J. Madsen; Guillermo J. Tearney; Bernard Choi; Haishan Zeng; Laura Marcu, Editor(s)

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