CdHgTe/SiO₂ nanoparticles were prepared by SiO₂ capping on the surface of CdHgTe quantum dots (QDs). The characteristics, such as optical spectra, size and optical stability were investigated. The size of CdHgTe/SiO₂ nanoparticles could be larger than 100 nm after CdHgTe QDs capped with SiO₂. CdHgTe/SiO₂ nanoparticles acted as a novel fluorescence probe have a maximum fluorescence emission of 790 nm and a full width at half-maximum (FWHM) of 50-70 nm. The in vivo fluorescence imaging of CdHgTe/SiO₂ nanoparticles in mouse model indicated the nanoparticles could be passively targeting to lung and liver. CdHgTe/SiO₂ nanoparticles offer new perspectives for size dependent bio-dstribution studies in living body.

Date Published: 11 February 2011
PDF: 10 pages
Proc. SPIE 7910, Reporters, Markers, Dyes, Nanoparticles, and Molecular Probes for Biomedical Applications III, 79100S (11 February 2011); doi: 10.1117/12.873350

Published in SPIE Proceedings Vol. 7910:
Reporters, Markers, Dyes, Nanoparticles, and Molecular Probes for Biomedical Applications III
Samuel Achilefu; Ramesh Raghavachari, Editor(s)