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Proceedings Paper

In vivo monitoring of organ-selective distribution of CdHgTe/SiO2 nanoparticles in mouse model
Author(s): Haiyan Chen; Sisi Cui; Hongyan Zhu; Zhenzhen Tu; Lingling Shan; Jianpeng Xue; Dawei Deng; Jun Zhang; Yueqing Gu
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Paper Abstract

CdHgTe/SiO2 nanoparticles were prepared by SiO2 capping on the surface of CdHgTe quantum dots (QDs). The characteristics, such as optical spectra, size and optical stability were investigated. The size of CdHgTe/SiO2 nanoparticles could be larger than 100 nm after CdHgTe QDs capped with SiO2. CdHgTe/SiO2 nanoparticles acted as a novel fluorescence probe have a maximum fluorescence emission of 790 nm and a full width at half-maximum (FWHM) of 50-70 nm. The in vivo fluorescence imaging of CdHgTe/SiO2 nanoparticles in mouse model indicated the nanoparticles could be passively targeting to lung and liver. CdHgTe/SiO2 nanoparticles offer new perspectives for size dependent bio-dstribution studies in living body.

Paper Details

Date Published: 11 February 2011
PDF: 10 pages
Proc. SPIE 7910, Reporters, Markers, Dyes, Nanoparticles, and Molecular Probes for Biomedical Applications III, 79100S (11 February 2011); doi: 10.1117/12.873350
Show Author Affiliations
Haiyan Chen, China Pharmaceutical Univ. (China)
Sisi Cui, China Pharmaceutical Univ. (China)
Hongyan Zhu, China Pharmaceutical Univ. (China)
Zhenzhen Tu, China Pharmaceutical Univ. (China)
Lingling Shan, China Pharmaceutical Univ. (China)
Jianpeng Xue, China Pharmaceutical Univ. (China)
Dawei Deng, China Pharmaceutical Univ. (China)
Jun Zhang, China Pharmaceutical Univ. (China)
Yueqing Gu, China Pharmaceutical Univ. (China)

Published in SPIE Proceedings Vol. 7910:
Reporters, Markers, Dyes, Nanoparticles, and Molecular Probes for Biomedical Applications III
Samuel Achilefu; Ramesh Raghavachari, Editor(s)

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