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Proceedings Paper

Dependence of third-harmonic generation on melanin concentration in solution
Author(s): Tung-Yu Su; Chien-Sheng Liao; Chih-Yuan Yang; Zong-Yan Zhuo; Szu-Yu Chen; Shi-Wei Chu
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Paper Abstract

In this study, we performed theoretical analysis and experimental measurement of third harmonic generation (THG) in melanin solution with different concentrations. As predicted by theory, only THG at glass/solution interface was observed due to Guoy phase shift effect. We have shown that this interfacial THG intensity is strongly affected by index matching condition between the two media, leading to minimal THG at a certain melanin concentration. By fitting the dependence of THG intensity versus melanin concentration, linear and nonlinear electric susceptibilities of melanin are obtained, providing a valuable tool to characterize optical properties of biological molecules.

Paper Details

Date Published: 11 February 2011
PDF: 5 pages
Proc. SPIE 7903, Multiphoton Microscopy in the Biomedical Sciences XI, 79030I (11 February 2011); doi: 10.1117/12.872837
Show Author Affiliations
Tung-Yu Su, National Taiwan Univ. (Taiwan)
Chien-Sheng Liao, National Taiwan Univ. (Taiwan)
Chih-Yuan Yang, National Taiwan Univ. (Taiwan)
Zong-Yan Zhuo, National Taiwan Univ. (Taiwan)
Szu-Yu Chen, National Taiwan Univ. (Taiwan)
Shi-Wei Chu, National Taiwan Univ. (Taiwan)

Published in SPIE Proceedings Vol. 7903:
Multiphoton Microscopy in the Biomedical Sciences XI
Ammasi Periasamy; Karsten König; Peter T. C. So, Editor(s)

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