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Proceedings Paper

Translating ultraviolet autofluorescence microscopy toward clinical endomicroscopy
Author(s): Bevin Lin; Shiro Urayama; Ramez M. G. Saroufeem; Dennis L. Matthews; Stavros G. Demos
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Paper Abstract

The potential of autofluorescence microscopy under ultraviolet excitation is investigated as a method to visualize superficial epithelial microstructures and their modification with progression of disease. This method does not require the use of contrast agents, sectioning methods, or tissue preparation. Imaging of esophagus tissue is the focus of this study and deals with three main issues: a) What is the origin of the signal; b) How the gradual microstructure modification associated with various stages of esophageal disease is visualized; c) What are the designing parameters for in vivo implementation.

Paper Details

Date Published: 16 February 2011
PDF: 9 pages
Proc. SPIE 7895, Optical Biopsy IX, 789502 (16 February 2011);
Show Author Affiliations
Bevin Lin, UC Davis Medical Ctr. (United States)
Shiro Urayama, UC Davis Medical Ctr. (United States)
Ramez M. G. Saroufeem, UC Davis Medical Ctr. (United States)
Dennis L. Matthews, UC Davis Medical Ctr. (United States)
Stavros G. Demos, UC Davis Medical Ctr. (United States)
Lawrence Livermore National Lab. (United States)

Published in SPIE Proceedings Vol. 7895:
Optical Biopsy IX
Robert R. Alfano, Editor(s)

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