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Proceedings Paper

Evaluation of microfluidic channels with optical coherence tomography
Author(s): J. Czajkowski; T. Prykäri; E. Alarousu; J. Lauri; R. Myllylä
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Paper Abstract

Application of time domain, ultra high resolution optical coherence tomography (UHR-OCT) in evaluation of microfluidic channels is demonstrated. Presented study was done using experimental UHR-OCT device based on a Kerr-lens mode locked Ti:sapphire femtosecond laser, a photonic crystal fibre and modified, free-space Michelson interferometer. To show potential of the technique, microfluidic chip fabricated by VTT Center for Printed Intelligence (Oulu, Finland) was measured. Ability for full volumetric reconstruction in non-contact manner enabled complete characterization of closed entity of a microfluidic channel without contamination and harm for the sample. Measurement, occurring problems, and methods of postprocessing for raw data are described. Results present completely resolved physical structure of the channel, its spatial dimensions, draft angles and evaluation of lamination quality.

Paper Details

Date Published: 24 November 2010
PDF: 9 pages
Proc. SPIE 7376, Laser Applications in Life Sciences, 737617 (24 November 2010); doi: 10.1117/12.871445
Show Author Affiliations
J. Czajkowski, Univ. of Oulu (Finland)
T. Prykäri, Univ. of Oulu (Finland)
E. Alarousu, King Abdullah Univ. of Science and Technology (Saudi Arabia)
J. Lauri, Univ. of Oulu (Finland)
R. Myllylä, Univ. of Oulu (Finland)

Published in SPIE Proceedings Vol. 7376:
Laser Applications in Life Sciences
Matti Kinnunen; Risto Myllylä, Editor(s)

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