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Proceedings Paper

New optical method for noninvasive blood glucose measurement by optical ultrasonic modulation
Author(s): Lili Zhu; Jieqing Lin; Wenming Xie; Hui Li
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Paper Abstract

A new optical technique for continuous, noninvasive monitoring of blood glucose levels based on ultrasonic modulation of scattering light is proposed. The ultrasound-modulated scattered light has an accurate separation of scattering and absorption changes in tissue. And the optical scattering and absorbing coefficient of tissue depend on the concentration of glucose in the extracellular fluid. As the glucose induced to scattering and absorption changes, the ultrasoundmodulated light also changes. In this paper, a correlation is observed between ultrasound-modulated light intensity as well as its modulation depth and blood glucose concentration in phantom experiments. In addition, some researches about ultrasound-modulated signal affected by the temperature of glucose aqueous solution are done. Preliminary experiments find that this method is a promising noninvasive blood glucose measurement.

Paper Details

Date Published: 8 November 2010
PDF: 6 pages
Proc. SPIE 7845, Optics in Health Care and Biomedical Optics IV, 784525 (8 November 2010); doi: 10.1117/12.869376
Show Author Affiliations
Lili Zhu, Fujian Normal Univ. (China)
Jieqing Lin, Fujian Normal Univ. (China)
Wenming Xie, Fujian Normal Univ. (China)
Hui Li, Fujian Normal Univ. (China)

Published in SPIE Proceedings Vol. 7845:
Optics in Health Care and Biomedical Optics IV
Qingming Luo; Ying Gu; Xingde Li, Editor(s)

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