
Proceedings Paper
Near-infrared autofluorescence imaging for colonic cancer detectionFormat | Member Price | Non-Member Price |
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Paper Abstract
We explore an NIR autofluorescence imaging technique for cancer diagnosis and detection. A set of tissue images
including NIR white light images, autofluorescence (AF) images and fluorescence polarized images (FPI) (parallel-, and
perpendicular- polarization) were acquired in tandem on human colonic tissues. The results show that NIR fluorescence
intensity of normal tissue is significantly higher than that of cancer tissue. The perpendicular-polarization image yields
the highest diagnostic accuracy 93% compared to other imaging modes. This work demonstrates that Fluorescence
polarization imaging (FPI) technique has great potential for cancer diagnosis and detection in the colon.
Paper Details
Date Published: 25 November 2009
PDF: 5 pages
Proc. SPIE 7634, Optical Sensors and Biophotonics, 76340B (25 November 2009); doi: 10.1117/12.852098
Published in SPIE Proceedings Vol. 7634:
Optical Sensors and Biophotonics
Xingde Li; Qingming Luo; Vasilis Ntziachristos; Yoshiaki Yasuno, Editor(s)
PDF: 5 pages
Proc. SPIE 7634, Optical Sensors and Biophotonics, 76340B (25 November 2009); doi: 10.1117/12.852098
Show Author Affiliations
Xiaozhuo Shao, National Univ. of Singapore (Singapore)
Wei Zheng, National Univ. of Singapore (Singapore)
Wei Zheng, National Univ. of Singapore (Singapore)
Zhiwei Huang, National Univ. of Singapore (Singapore)
Published in SPIE Proceedings Vol. 7634:
Optical Sensors and Biophotonics
Xingde Li; Qingming Luo; Vasilis Ntziachristos; Yoshiaki Yasuno, Editor(s)
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