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Proceedings Paper

A combined voxel and surface based method for topology correction of brain surfaces
Author(s): Florence Gris; Jean-Marie Favreau; Oscar Acosta; Vincent Barra; Olivier Salvado
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Paper Abstract

Brain surfaces provide a reliable representation for cortical mapping. The construction of correct surfaces from magnetic resonance images (MRI) segmentation is a challenging task, especially when genus zero surfaces are required for further processing such as parameterization, partial inflation and registration. The generation of such surfaces has been approached either by correcting a binary image as part of the segmentation pipeline or by modifying the mesh representing the surface. During this task, the preservation of the structure may be compromised because of the convoluted nature of the brain and noisy/imperfect segmentations. In this paper, we propose a combined, voxel and surfacebased, topology correction method which preserves the structure of the brain while yielding genus zero surfaces. The topology of the binary segmentation is first corrected using a set of topology preserving operators applied sequentially. This results in a white matter/gray matter binary set with correct sulci delineation, homotopic to a filled sphere. Using the corrected segmentation, a marching cubes mesh is then generated and the tunnels and handles resulting from the meshing are finally removed with an algorithm based on the detection of nonseparating loops. The approach was validated using 20 young individuals MRI from the OASIS database, acquired at two different time-points. Reproducibility and robustness were evaluated using global and local criteria such as surface area, curvature and point to point distance. Results demonstrated the method capability to produce genus zero meshes while preserving geometry, two fundamental properties for reliable and accurate cortical mapping and further clinical studies.

Paper Details

Date Published: 12 March 2010
PDF: 12 pages
Proc. SPIE 7623, Medical Imaging 2010: Image Processing, 76234T (12 March 2010); doi: 10.1117/12.844624
Show Author Affiliations
Florence Gris, Australian e-Health Research Ctr. (Australia)
Ecole Nationale Supérieure de Physique de Strasbourg (France)
Univ. de Strasbourg (France)
Jean-Marie Favreau, Univ. Blaise Pascal (France)
Oscar Acosta, Australian e-Health Research Ctr. (Australia)
Vincent Barra, Univ. Blaise Pascal (France)
Olivier Salvado, Australian e-Health Research Ctr. (Australia)

Published in SPIE Proceedings Vol. 7623:
Medical Imaging 2010: Image Processing
Benoit M. Dawant; David R. Haynor, Editor(s)

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