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Proceedings Paper

Dynamic CT head phantom for perfusion and angiography studies
Author(s): K. Russell; A. Blazeski; K. Dannecker; Q. Y. Lee; C. Holscher; C. Donahue; W. van Kampen
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Paper Abstract

Contrast imaging is a compelling enhancement for the portable, flat panel-based brain CT scanner currently under development at Xoran. Due to the relative low temporal resolution of flat panel detectors, enabling tomographic imaging on such platform requires optimizing the imaging and injection protocols. A dynamic CT head phantom was designed to facilitate this task. The Dynamic Perfusion and Angiography Model (PAM), mimics tissue attenuation in CT images, provides physiological timing for angiography and perfusion studies, and moves fluid with properties similar to those of blood. The design consists of an arterial system, which contains bifurcating vessels that feed into perfusion chambers, mimicking blood flow through capillaries and smaller vessels, and a venous system, which is symmetrical to the arterial side and drains the perfusion chambers. The variation of geometry and flow rate in the phantom provides the physiological total time that fluid spends in the head, and the difference in material densities correlates to CT numbers for biological tissues. This paper discusses the design of Dynamic PAM and shows experimental results demonstrating its ability to realistically simulate blood flow. Results of dynamic imaging studies of the phantom are also presented.

Paper Details

Date Published: 18 March 2010
PDF: 5 pages
Proc. SPIE 7626, Medical Imaging 2010: Biomedical Applications in Molecular, Structural, and Functional Imaging, 76261Y (18 March 2010); doi: 10.1117/12.844474
Show Author Affiliations
K. Russell, Univ. of Michigan (United States)
A. Blazeski, Univ. of Michigan (United States)
K. Dannecker, Univ. of Michigan (United States)
Q. Y. Lee, Univ. of Michigan (United States)
C. Holscher, Univ. of Michigan (United States)
C. Donahue, Univ. of Michigan (United States)
W. van Kampen, Xoran Technologies, Inc. (United States)

Published in SPIE Proceedings Vol. 7626:
Medical Imaging 2010: Biomedical Applications in Molecular, Structural, and Functional Imaging
Robert C. Molthen; John B. Weaver, Editor(s)

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