Share Email Print
cover

Proceedings Paper

Prediction of sensitivity thresholds in optoacoustic tomography
Author(s): Daniel Razansky; John Baeten; Vasilis Ntziachristos
Format Member Price Non-Member Price
PDF $17.00 $21.00

Paper Abstract

Since optoacoustic tomography is considered a high-resolution modality, determination of the absolute detection limit, as it relates to the sensitivity of biomarker detection is not straightforward. This is due to the fact that experimental determination of the sensitivity as a function of target size remains difficult since no established technique exists so far to reproducibly create very small targets containing well-defined concentrations of markers. We combine theoretical analysis with imaging results for large amounts of the marker and place the measured value on the appropriate parameter-dependent signal intensity curve. A performance estimate of the particular experimental system and the expected signal-to-noise-ratio for smaller amounts of markers can then be made.

Paper Details

Date Published: 23 February 2010
PDF: 5 pages
Proc. SPIE 7564, Photons Plus Ultrasound: Imaging and Sensing 2010, 75640L (23 February 2010); doi: 10.1117/12.843256
Show Author Affiliations
Daniel Razansky, Technische Univ. München (Germany)
Helmholtz Zentrum München GmbH (Germany)
John Baeten, Technische Univ. München (Germany)
Helmholtz Zentrum München GmbH (Germany)
Vasilis Ntziachristos, Technische Univ. München (Germany)
Helmholtz Zentrum München GmbH (Germany)


Published in SPIE Proceedings Vol. 7564:
Photons Plus Ultrasound: Imaging and Sensing 2010
Alexander A. Oraevsky; Lihong V. Wang, Editor(s)

© SPIE. Terms of Use
Back to Top