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Proceedings Paper

Guided-mode resonance sensor system for early detection of ovarian cancer
Author(s): Debra Wawro; Peter Koulen; Yiwu Ding; Shelby Zimmerman; Robert Magnusson
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Paper Abstract

A high-accuracy sensor system has been developed that provides near-instantaneous detection of biomarker proteins as indicators of ovarian serous papillary carcinoma. Based upon photonic guided-mode resonance technology, these highresolution sensors employ multiple resonance peaks to rapidly test for relevant proteins in complex biological samples. This label-free sensor approach requires minimal sample processing and has the capability to measure multiple agents simultaneously and in real time. A detection system has been developed and performance characterized. Identification and quantification of protein biomarkers that are up- or downregulated in blood and serum as indicators of ovarian cancer will be presented.

Paper Details

Date Published: 25 February 2010
PDF: 6 pages
Proc. SPIE 7572, Optical Diagnostics and Sensing X: Toward Point-of-Care Diagnostics, 75720D (25 February 2010); doi: 10.1117/12.842725
Show Author Affiliations
Debra Wawro, Resonant Sensors Inc. (United States)
Peter Koulen, Univ. of Missouri (United States)
Yiwu Ding, Resonant Sensors Inc. (United States)
Shelby Zimmerman, Resonant Sensors Inc. (United States)
Robert Magnusson, Resonant Sensors Inc. (United States)
Univ. of Texas at Arlington (United States)

Published in SPIE Proceedings Vol. 7572:
Optical Diagnostics and Sensing X: Toward Point-of-Care Diagnostics
Gerard L. Coté, Editor(s)

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