
Proceedings Paper
Experimental and theoretical investigation of capillary flow with BSA and microbead suspensionsFormat | Member Price | Non-Member Price |
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Paper Abstract
The present study reports an investigation of capillary transport with a suspension of microbeads and biomolecules.
Series of experiments are performed to deduce the concentration based surface tension and contact angle expression
for microbead and biomolecule suspension. It is observed that, the microbead suspension restricts the
spreading of the fluid front. Hence a decrease in the surface tension and an increase in the contact angle is
observed as the concentration of suspension is increased. Different expressions for contact angle and surface
tension depending on the range of the microbead concentrations are deduced. Theoretical model to predict the
capillary transport in rectangular microchannel considering the change in physical and surface properties of the
fluid is developed. The capillary transport in a microfabricated silicon microchannel is observed for fluid with
and without microbead. Theoretical and experimental observations match quite well, whereas the quantitative
difference in case of transport with microbead suspension is observed. Thus, the effect of suspension on the fluid
properties can not be neglected in a capillary transport.
Paper Details
Date Published: 17 February 2010
PDF: 9 pages
Proc. SPIE 7593, Microfluidics, BioMEMS, and Medical Microsystems VIII, 75930O (17 February 2010); doi: 10.1117/12.842215
Published in SPIE Proceedings Vol. 7593:
Microfluidics, BioMEMS, and Medical Microsystems VIII
Holger Becker; Wanjun Wang, Editor(s)
PDF: 9 pages
Proc. SPIE 7593, Microfluidics, BioMEMS, and Medical Microsystems VIII, 75930O (17 February 2010); doi: 10.1117/12.842215
Show Author Affiliations
Prashant R. Waghmare, Univ. of Alberta (Canada)
Sushanta K. Mitra, Univ. of Alberta (Canada)
Published in SPIE Proceedings Vol. 7593:
Microfluidics, BioMEMS, and Medical Microsystems VIII
Holger Becker; Wanjun Wang, Editor(s)
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