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Proceedings Paper

In vivo detection of time-resolved singlet oxygen luminescence under PDT relevant conditions
Author(s): Jan Schlothauer; Beate Röder; Steffen Hackbarth; Jürgen Lademann
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Paper Abstract

For the fist time worldwide we report high amplitude NIR-Luminescence signals, measured in pig skin. The measurements are achieved with a recently developed setup that was shown to provide superior performance for 1O2- luminescence detection in vitro. This setup has been adapted to allow now the detection of singlet oxygen signals in vivo. Pig ears were used for first measurements as a widely accepted in vivo model for human skin.

Paper Details

Date Published: 2 March 2010
PDF: 9 pages
Proc. SPIE 7551, Optical Methods for Tumor Treatment and Detection: Mechanisms and Techniques in Photodynamic Therapy XIX, 755106 (2 March 2010); doi: 10.1117/12.839851
Show Author Affiliations
Jan Schlothauer, Humboldt-Univ. zu Berlin (Germany)
Beate Röder, Humboldt-Univ. zu Berlin (Germany)
Steffen Hackbarth, Humboldt-Univ. zu Berlin (Germany)
Jürgen Lademann, Charité Universitätsmedizin Berlin (Germany)


Published in SPIE Proceedings Vol. 7551:
Optical Methods for Tumor Treatment and Detection: Mechanisms and Techniques in Photodynamic Therapy XIX
David H. Kessel, Editor(s)

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