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Proceedings Paper

Incidence and significance of the pseudo stent strut in optical coherence tomography analysis for coronary artery stents
Author(s): Nobuaki Suzuki; Ken Kozuma; Taketo Hatsuno; Kaoru Takada; Ryu Iino; Yoshio Maeno; Hirosada Yamamoto; Yoshitaka Shiratori; Shuichi Ishikawa; Akiyoshi Miyazawa; Takaaki Isshiki
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Paper Abstract

Introduction: Quantitative optical coherence tomography (OCT) analysis is about to be relevant for the correct assessment of incomplete stent apposition which can result to late stent thrombosis. Nevertheless, the pseudo stent struts (PS), which show the strong signal same as the true strut, are sometimes seen at odd positions in the lumen and locate at the same distance from the image wire as a true strut. PS may be produced by the distorted beam and interfere accurate analysis. Our aim was to investigate the incidence of PS. Methods: We created a simple phantom model (2.5 mm-coronary artery stent apposed in 2.5-mm silicon tube). OCT pullback images at 1 mm/sec were obtained with an eccentric imagewire position for 5 times with different 5 pieces of imagewire. The strut location was recognized by the strong signal. Of these, PS was defined as: an irregularity of the alignment of strut locations; the difference in the strut-wire distance with one of the adjacent struts is within 20 micron. Strut contour with and without PS were delineated by semi-automated dedicated software with cubic spline interpolation, and symmetry index (= Min/Max diameter) was calculated. Results: In the phantom with Cypher stent and Tsunami stent, a pseudo strut reflection was observed in 71 of 7112 (1%) frames and 43 of 10302 (0.4%) frames, respectively. The PS incidence was the highest at fifth pull-back images. The symmetry index was significantly higher in strut contours without pseudo strut (0.95±0.02 versus 0.83±0.07, p<0.001). Conclusion: PS may mislead to the wrong data of clinical OCT analysis, in spite of the infrequency. When one starts to use the new image modality, one should be careful if there is some artifact which can affect on the data of the clinical investigations.

Paper Details

Date Published: 2 March 2010
PDF: 8 pages
Proc. SPIE 7548, Photonic Therapeutics and Diagnostics VI, 75483D (2 March 2010); doi: 10.1117/12.839836
Show Author Affiliations
Nobuaki Suzuki, Teikyo Univ. School of Medicine (Japan)
Ken Kozuma, Teikyo Univ. School of Medicine (Japan)
Taketo Hatsuno, Teikyo Univ. School of Medicine (Japan)
Kaoru Takada, Teikyo Univ. School of Medicine (Japan)
Ryu Iino, Teikyo Univ. School of Medicine (Japan)
Yoshio Maeno, Teikyo Univ. School of Medicine (Japan)
Hirosada Yamamoto, Teikyo Univ. School of Medicine (Japan)
Yoshitaka Shiratori, Teikyo Univ. School of Medicine (Japan)
Shuichi Ishikawa, Teikyo Univ. School of Medicine (Japan)
Akiyoshi Miyazawa, Teikyo Univ. School of Medicine (Japan)
Takaaki Isshiki, Teikyo Univ. School of Medicine (Japan)

Published in SPIE Proceedings Vol. 7548:
Photonic Therapeutics and Diagnostics VI
Anita Mahadevan-Jansen; Andreas Mandelis; Brian Jet-Fei Wong M.D.; Nikiforos Kollias; Henry Hirschberg M.D.; Kenton W. Gregory M.D.; Reza S. Malek; E. Duco Jansen; Guillermo J. Tearney; Steen J. Madsen; Bernard Choi; Justus F. R. Ilgner; Haishan Zeng; Laura Marcu, Editor(s)

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