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Proceedings Paper

Knowledge discovery in ophthalmology: analysis of wet form of age-related macular degeneration treatment outcomes
Author(s): Magdalena Ulińska; Emanuel Tataj; Jan J. Mulawka; Jerzy Szaflik
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Paper Abstract

Age-related Macular Degeneration (AMD), according to epidemiological data, is a main reason of social blindness among elderly people in developed countries. There are two forms of AMD: dry and wet. The first one is of good prognosis with low possibility of serious visual deterioration, while the second one usually leads to quick and severe visual impairment. The aim of our investigations is to analyse results of so called real-life treatment of wet AMD. We analysed outcomes of our patients treated with intravitreal injections of anti-VEGF drugs: Lucentis (61 patients) and Avastin (78 patients). We analysed changes in visual acuity (functional effect) and central retinal thickness (anatomic effect). Both drugs occurred to be efficient in treatment of wet form of AMD, however results were more satisfying in patients with better baseline visual acuity. In our approach we used R environment - an integrated suite of software facilities for data analysis and graphics.

Paper Details

Date Published: 5 August 2009
PDF: 10 pages
Proc. SPIE 7502, Photonics Applications in Astronomy, Communications, Industry, and High-Energy Physics Experiments 2009, 75022H (5 August 2009); doi: 10.1117/12.838221
Show Author Affiliations
Magdalena Ulińska, Warsaw Medical Univ. (Poland)
Emanuel Tataj, Warsaw Univ. of Technology (Poland)
Jan J. Mulawka, Warsaw Univ. of Technology (Poland)
Jerzy Szaflik, Warsaw Medical Univ. (Poland)


Published in SPIE Proceedings Vol. 7502:
Photonics Applications in Astronomy, Communications, Industry, and High-Energy Physics Experiments 2009
Ryszard S. Romaniuk; Krzysztof S. Kulpa, Editor(s)

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