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Proceedings Paper

Surface plasmon resonance biosensors: advances and applications
Author(s): Jirí Homola
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Paper Abstract

Surface plasmon resonance (SPR) biosensors represent the most advanced label-free optical affinity biosensor technology. In the last decade numerous SPR sensor platforms have been developed and applied in the life sciences and bioanalytics. This contribution reviews the state of the art in the development of SPR (bio)sensor technology and presents selected results of research into SPR biosensors at the Institute of Photonics and Electronics, Prague. The developments discussed in detail include a miniature fiber optic SPR sensor for localized measurements, a compact SPR sensor for field use and a multichannel SPR sensor for high-throughput screening. Examples of applications for the detection of analytes related to medical diagnostics (biomarkers, hormones, antibodies), environmental monitoring (endocrine disrupting compounds), and food safety (pathogens and toxins) are given.

Paper Details

Date Published: 5 October 2009
PDF: 4 pages
Proc. SPIE 7503, 20th International Conference on Optical Fibre Sensors, 75030P (5 October 2009); doi: 10.1117/12.837626
Show Author Affiliations
Jirí Homola, Institute of Photonics and Electronics (Czech Republic)

Published in SPIE Proceedings Vol. 7503:
20th International Conference on Optical Fibre Sensors
Julian D. C. Jones, Editor(s)

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