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Proceedings Paper

Multispectral autofluorescence diagnosis of non-melanoma cutaneous tumors
Author(s): Ekaterina Borisova; Daniela Dogandjiiska; Irina Bliznakova; Latchezar Avramov; Elmira Pavlova; Petranka Troyanova
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Paper Abstract

Fluorescent analysis of basal cell carcinoma (BCC), squamous cell carcinoma (SCC), keratoacanthoma and benign cutaneous lesions is carried out under initial phase of clinical trial in the National Oncological Center - Sofia. Excitation sources with maximum of emission at 365, 380, 405, 450 and 630 nm are applied for better differentiation between nonmelanoma malignant cutaneous lesions fluorescence and spectral discrimination from the benign pathologies. Major spectral features are addressed and diagnostic discrimination algorithms based on lesions' emission properties are proposed. The diagnostic algorithms and evaluation procedures found will be applied for development of an optical biopsy clinical system for skin cancer detection in the frames of National Oncological Center and other university hospital dermatological departments in our country.

Paper Details

Date Published: 7 July 2009
PDF: 6 pages
Proc. SPIE 7368, Clinical and Biomedical Spectroscopy, 736823 (7 July 2009); doi: 10.1117/12.831563
Show Author Affiliations
Ekaterina Borisova, Institute of Electronics (Bulgaria)
Daniela Dogandjiiska, Institute of Electronics (Bulgaria)
Sofia Univ. (Bulgaria)
Irina Bliznakova, Institute of Electronics (Bulgaria)
Latchezar Avramov, Institute of Electronics (Bulgaria)
Elmira Pavlova, National Oncological Ctr. (Bulgaria)
Univ. Hospital for Active Treatment in Oncology (Bulgaria)
Petranka Troyanova, Univ. Hospital for Active Treatment in Oncology (Bulgaria)

Published in SPIE Proceedings Vol. 7368:
Clinical and Biomedical Spectroscopy
Irene Georgakoudi; Jürgen Popp; Katarina Svanberg M.D., Editor(s)

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