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Proceedings Paper

Seeing the light: a photonic visual prosthesis for the blind
Author(s): Patrick Degenaar; Nir Grossman; Brian McGovern; Mark Neil; Emmanuel Drakakis; Konstantin Nikolic
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Paper Abstract

This paper highlights how the genetic incorporation of artificial opsins into the retina can lead to a new class of retinal prosthesis. We demonstrate the efficacy of incorporating channelrhodopsin into neuron cells in-vitro and show how that can be scaled to in-vivo. We show that we need typically 100mW/cm2 of instantaneous light intensity on the neuron in order to stimulate action potentials which results in 10W/cm2 required from the light source. We thus use GaN LED arrays to provide spatially controlled stimulation which is of sufficient brightness to stimulate the cells.

Paper Details

Date Published: 23 February 2009
PDF: 11 pages
Proc. SPIE 7180, Photons and Neurons, 71800I (23 February 2009); doi: 10.1117/12.823577
Show Author Affiliations
Patrick Degenaar, Imperial College (United Kingdom)
Nir Grossman, Imperial College (United Kingdom)
Brian McGovern, Imperial College (United Kingdom)
Mark Neil, Imperial College (United Kingdom)
Emmanuel Drakakis, Imperial College (United Kingdom)
Konstantin Nikolic, Imperial College (United Kingdom)

Published in SPIE Proceedings Vol. 7180:
Photons and Neurons
Anita Mahadevan-Jansen; E. Duco Jansen, Editor(s)

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