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Proceedings Paper

Broadband transmission spectroscopy in tissue: application to radiofrequency tissue fusion
Author(s): Timmy Floume; Richard R. A. Syms; Ara W. Darzi; George B. Hanna
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Paper Abstract

Radiofrequency tissue fusion consists in heating apposed tissue faces, which results in their sealing. Tissue transformations must be controlled to obtain reliable reproducible seal. In this paper we demonstrate how to extract information on the two main tissue transformations, thermal damage and dehydration, from continuous wave transmission spectra. A fibre based near infrared transmission spectroscopy system is presented and described theoretically. Show demonstrate that such system can be fully modeled using ray optics considerations for the coupling of the light into optical fibers, and MC simulations of light propagation in tissue. We then develop an algorithm based on the absolute measurement of attenuation and the modified Beer Lambert Law that enables the extraction of absolute tissue hydration and information on the degree of thermal damage, via scattering losses. We also discuss the basis and limit of absolute measurement during broadband submicronic tissue transmittance spectroscopy.

Paper Details

Date Published: 18 May 2009
PDF: 12 pages
Proc. SPIE 7356, Optical Sensors 2009, 73562C (18 May 2009); doi: 10.1117/12.823091
Show Author Affiliations
Timmy Floume, Imperial College London (United Kingdom)
Richard R. A. Syms, Imperial College London (United Kingdom)
Ara W. Darzi, St. Mary's Hospital, Imperial College London (United Kingdom)
George B. Hanna, St. Mary's Hospital, Imperial College London (United Kingdom)

Published in SPIE Proceedings Vol. 7356:
Optical Sensors 2009
Francesco Baldini; Jiri Homola; Robert A. Lieberman, Editor(s)

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