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Proceedings Paper

Characterization for organic ion-sensitive field effect transistor response for measurement of physiological potassium ion-concentration measurement
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Paper Abstract

Potassium ion monitoring, in human body, is important for diagnostic and therapeutic purposes. The dynamic response of potassium selective ISFET sensors is instrumental in formulating calibration schema and signal compensations to correct systematic errors. In the research reported here, response characteristics of potassium selective ISFETs were studied. The range of detection was set between 1mM and 25mM to cover all the physiological potassium concentrations. The signals were obtained from an array of sensors, with different aspect ratios, by varying potassium ion concentrations in a time dependent fashion. Normalization of the drain current was used to compensation for variance in order of magnitude observed in different sensors. Sensor response time and linear response range were analyzed, in relation to difference in aspect ratios. Probable modifications in calibration scheme and compensation technique, subjective to the findings, have been suggested.

Paper Details

Date Published: 31 March 2009
PDF: 9 pages
Proc. SPIE 7291, Nanosensors, Biosensors, and Info-Tech Sensors and Systems 2009, 72910H (31 March 2009); doi: 10.1117/12.821555
Show Author Affiliations
Pratysh Rai, Univ. of Arkansas (United States)
Soyoun Jung, Univ. of Arkansas (United States)
Taeksoo Ji, Univ. of Arkansas (United States)
Vijay K. Varadan, Univ. of Arkansas (United States)

Published in SPIE Proceedings Vol. 7291:
Nanosensors, Biosensors, and Info-Tech Sensors and Systems 2009
Vijay K. Varadan, Editor(s)

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