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Proceedings Paper

Photonic crystal slab and waveguide design for biological detection
Author(s): Elizabeth Tanner; Juronica Arch; Anne-Marie Dorsett; Derek Strembicke; Milan Buncick; Jian Han; Scott Retterer; Darrell Thomas
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Paper Abstract

In this work we have designed, fabricated, and tested a photonic crystal slab (PCS) with a line defect waveguide for the detection and identification of pathogenic DNA. A PCS is constructed by fabricating a material with 2-dimensional dielectric periodicity sandwiched between two semi-infinite cladding regions of lower effective index [1]. In order to uniquely identify pathogens critical to medical and homeland defense applications, the PCS was functionalized with a single stranded probe molecule providing highly specific binding for the target DNA. Integrated microfluidic channels provide delivery of the pathogen DNA resulting in hybridization and binding in the PCS holes. The binding event changes the refractive index of the PCS which results in a measurable change in the transmitted power. We will discuss design parameters and the suite of modeling tools used to optimize the PCS, defect waveguide, and coupling devices. An overview of the fabrication methods and tools will be provided and we will also report preliminary experimental results.

Paper Details

Date Published: 30 April 2009
PDF: 10 pages
Proc. SPIE 7322, Photonic Microdevices/Microstructures for Sensing, 73220B (30 April 2009); doi: 10.1117/12.818644
Show Author Affiliations
Elizabeth Tanner, Kratos Defense and Security Solutions (United States)
Juronica Arch, Kratos Defense and Security Solutions (United States)
Anne-Marie Dorsett, Kratos Defense and Security Solutions (United States)
Derek Strembicke, AEgis Technologies Group, Inc. (United States)
Milan Buncick, AEgis Technologies Group, Inc. (United States)
Jian Han, HudsonAlpha Institute for Biotechnology (United States)
Scott Retterer, Ctr. for Nanophase Materials Sciences, Oak Ridge National Lab. (United States)
Darrell Thomas, Ctr. for Nanophase Materials Sciences, Oak Ridge National Lab. (United States)

Published in SPIE Proceedings Vol. 7322:
Photonic Microdevices/Microstructures for Sensing
Hai Xiao; Xudong Fan; Anbo Wang, Editor(s)

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