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Proceedings Paper

Visualization and enhancement patterns of radiofrequency ablation lesions with iodine contrast-enhanced cardiac C-arm CT
Author(s): Erin Girard-Hughes; Amin Al-Ahmad; Teri Moore; Günter Lauritsch; Jan Boese; Rebecca Fahrig
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Paper Abstract

The purpose of this study was to evaluate whether contrast-enhanced C-arm CT (3D rotational angiography) can distinguish radiofrequency (RF) ablation lesions created in the left ventricle. Ablation lesions were created on the endocardial surface of the left ventricle of 6 swine using a 7 F RF ablation catheter with a 4 mm electrode. An ECGgated C-arm CT imaging protocol was used to acquire projection images during iodine contrast injection and every 5 min for up to 30 min, with no additional contrast. Reconstructed images were analyzed offline and the mean and standard deviation of the signal intensity of the ablation lesion, normal myocardium, and blood were measured. Eleven ablation lesions were visualized and the time-attenuation curve of the signal intensity was plotted. A mean signal intensity increase of 64.8 ±33.6 HU was measured in the late enhancement of seven lesions compared to normal myocardium. This is the first study to demonstrate RF ablation lesion enhancement patterns similar to those seen for MR imaging using C-arm CT, an imaging modality that can provide valuable feedback during cardiac interventional procedures.

Paper Details

Date Published: 27 February 2009
PDF: 9 pages
Proc. SPIE 7262, Medical Imaging 2009: Biomedical Applications in Molecular, Structural, and Functional Imaging, 72621N (27 February 2009); doi: 10.1117/12.812947
Show Author Affiliations
Erin Girard-Hughes, Stanford Univ. (United States)
Amin Al-Ahmad, Stanford Univ. (United States)
Teri Moore, Siemens Medical Solutions USA, Inc. (United States)
Günter Lauritsch, Siemens AG, Healthcare Sector (Germany)
Jan Boese, Siemens AG, Healthcare Sector (Germany)
Rebecca Fahrig, Stanford Univ. (United States)

Published in SPIE Proceedings Vol. 7262:
Medical Imaging 2009: Biomedical Applications in Molecular, Structural, and Functional Imaging
Xiaoping P. Hu; Anne V. Clough, Editor(s)

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