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Proceedings Paper

Quantitative measurement and analysis for detection and treatment planning of developmental dysplasia of the hip
Author(s): Xin Liu; Hongbing Lu; Hanyong Chen; Li Zhao; Zhengxing Shi; Zhengrong Liang
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Paper Abstract

Developmental dysplasia of the hip is a congenital hip joint malformation affecting the proximal femurs and acetabulum that are subluxatable, dislocatable, and dislocated. Conventionally, physicians made diagnoses and treatments only based on findings from two-dimensional (2D) images by manually calculating clinic parameters. However, anatomical complexity of the disease and the limitation of current standard procedures make accurate diagnosis quite difficultly. In this study, we developed a system that provides quantitative measurement of 3D clinical indexes based on computed tomography (CT) images. To extract bone structure from surrounding tissues more accurately, the system firstly segments the bone using a knowledge-based fuzzy clustering method, which is formulated by modifying the objective function of the standard fuzzy c-means algorithm with additive adaptation penalty. The second part of the system calculates automatically the clinical indexes, which are extended from 2D to 3D for accurate description of spatial relationship between femurs and acetabulum. To evaluate the system performance, experimental study based on 22 patients with unilateral or bilateral affected hip was performed. The results of 3D acetabulum index (AI) automatically provided by the system were validated by comparison with 2D results measured by surgeons manually. The correlation between the two results was found to be 0.622 (p<0.01).

Paper Details

Date Published: 27 February 2009
PDF: 8 pages
Proc. SPIE 7260, Medical Imaging 2009: Computer-Aided Diagnosis, 72603N (27 February 2009); doi: 10.1117/12.811531
Show Author Affiliations
Xin Liu, Fourth Military Medical Univ. (China)
Tsinghua Univ. (China)
Hongbing Lu, Fourth Military Medical Univ. (China)
Hanyong Chen, Fourth Military Medical Univ. (China)
Li Zhao, Xinhua Hospital, Shanghai Jiaotong Univ. (China)
Zhengxing Shi, Fourth Military Medical Univ. (China)
Zhengrong Liang, SUNY, Stony Brook (United States)

Published in SPIE Proceedings Vol. 7260:
Medical Imaging 2009: Computer-Aided Diagnosis
Nico Karssemeijer; Maryellen L. Giger, Editor(s)

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