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Proceedings Paper

Endoscopic photoacoustic microscopy
Author(s): Joon-Mo Yang; Konstantin Maslov; Hao-Chung Yang; Qifa Zhou; Lihong V. Wang
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Paper Abstract

We present a concept and system implementation for endoscopic photoacoustic microscopy that enables minimally invasive diagnosis of internal organs. The system incorporates an in-house made single element ultrasonic transducer for photoacoustic signal detection and an optical fiber for light delivery into a tubular probe with a mechanical scanning unit. The implemented probe size for the distal end is 4.2 mm in diameter and 48 mm in length. We evaluated the system's performance by imaging a carbon fiber in clear and turbid media. We also demonstrated its ability to image actual biological tissues and its endoscopic applicability, by imaging abdominal surfaces and a large intestinal tract of a rat ex vivo. This study shows the system's potential for in vivo optical biopsy of tissue abnormalities, such as tumors, developed in internal organs.

Paper Details

Date Published: 24 February 2009
PDF: 9 pages
Proc. SPIE 7177, Photons Plus Ultrasound: Imaging and Sensing 2009, 71770N (24 February 2009); doi: 10.1117/12.810952
Show Author Affiliations
Joon-Mo Yang, Washington Univ. in St. Louis (United States)
Konstantin Maslov, Washington Univ. in St. Louis (United States)
Hao-Chung Yang, Univ. of Southern California (United States)
Qifa Zhou, Univ. of Southern California (United States)
Lihong V. Wang, Washington Univ. in St. Louis (United States)

Published in SPIE Proceedings Vol. 7177:
Photons Plus Ultrasound: Imaging and Sensing 2009
Alexander A. Oraevsky; Lihong V. Wang, Editor(s)

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