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Proceedings Paper

Optoacoustic detection of thermal lesions
Author(s): Michel G. Arsenault; Michael C. Kolios; William M. Whelan
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Paper Abstract

Minimally invasive thermal therapy is being investigated as an alternative cancer treatment. It involves heating tissues to greater than 55°C over a period of a few minutes, which results in tissue coagulation. Optoacoustic (OA) imaging is a new imaging technique that involves exposing tissues to pulsed light and detecting the acoustic waves that are generated. In this study, adult bovine liver tissue samples were heated using continuous wave laser energy for various times, then scanned using an optoacoustic imaging system. Large optoacoustic signal variability was observed in the native tissue prior to heating. OA signal amplitude increased with maximum tissue temperature achieved, characterized by a correlation coefficient of 0.63. In this study we show that there are detectable changes in optoacoustic signal strength that arise from tissue coagulation, which demonstrates the potential of optoacoustic technology for the monitoring of thermal therapy delivery.

Paper Details

Date Published: 24 February 2009
PDF: 7 pages
Proc. SPIE 7177, Photons Plus Ultrasound: Imaging and Sensing 2009, 71771V (24 February 2009); doi: 10.1117/12.810913
Show Author Affiliations
Michel G. Arsenault, Univ. of Prince Edward Island (Canada)
Michael C. Kolios, Ryerson Univ. (Canada)
William M. Whelan, Univ. of Prince Edward Island (Canada)
Atlantic Veterinary College (Canada)

Published in SPIE Proceedings Vol. 7177:
Photons Plus Ultrasound: Imaging and Sensing 2009
Alexander A. Oraevsky; Lihong V. Wang, Editor(s)

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