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Proceedings Paper

Simultaneous imaging of ultrasound attenuation, speed of sound, and optical absorption in a photoacoustic setup
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Paper Abstract

Photoacoustic imaging is a relatively new medical imaging modality. In principle it can be used to image the optical absorption distribution of an object by measurements of optically induced acoustic signals. Recently we have developed a modified photoacoustic measurement system which can be used to simultaneously image the ultrasound propagation parameters as well. By proper placement of a passive element we obtain isolated measurements of the object's ultrasound propagation parameters, independent of the optical absorption inside the object. This passive element acts as a photoacoustic source and measurements are obtained by allowing the generated ultrasound signal to propagate through the object. Images of the ultrasound propagation parameters, being the attenuation and speed of sound, can then be reconstructed by inversion of a measurement model. This measurement model relates the projections non-linearly to the unknown images, due to ray refraction effects. After estimating the speed of sound and attenuation distribution, the optical absorption distribution is reconstructed. In this reconstruction problem we take into account the previously estimated speed of sound distribution. So far, the reconstruction algorithms have been tested using computer simulations. The method has been compared with existing algorithms and good results have been obtained.

Paper Details

Date Published: 13 March 2009
PDF: 10 pages
Proc. SPIE 7265, Medical Imaging 2009: Ultrasonic Imaging and Signal Processing, 72650J (13 March 2009); doi: 10.1117/12.810905
Show Author Affiliations
Rene G. H. Willemink, Univ. of Twente (Netherlands)
Srirang Manohar, Univ. of Twente (Netherlands)
Jithin Jose, Univ. of Twente (Netherlands)
Kees Slump, Univ. of Twente (Netherlands)
Ferdi van der Heijden, Univ. of Twente (Netherlands)
Ton G. van Leeuwen, Univ. of Twente (Netherlands)

Published in SPIE Proceedings Vol. 7265:
Medical Imaging 2009: Ultrasonic Imaging and Signal Processing
Stephen A. McAleavey; Jan D'hooge, Editor(s)

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