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Proceedings Paper

Preliminary study report: topological texture features extracted from standard radiographs of the heel bone are correlated with femoral bone mineral density
Author(s): H. F. Boehm; J. Lutz; M. Koerner; M. Notohamiprodjo; M. Reiser
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Paper Abstract

With the growing number of eldery patients in industrialized nations the incidence of geriatric, i.e. osteoporotic fractures is steadily on the rise. It is of great importance to understand the characteristics of hip fractures and to provide diagnostic tests for the assessment of an individual's fracture-risk that allow to take preventive action and give therapeutic advice. At present, bone-mineral-density (BMD) obtained from DXA (dual-energy x-ray-absorptiometry) is the clinical standard of reference for diagnosis and follow-up of osteoporosis. Since availability of DXA - other than that of clinical X-ray imaging - is usually restricted to specialized medical centers it is worth trying to implement alternative methods to estimate an individual's BMD. Radiographs of the peripheral skeleton, e.g. the ankle, range among the most ordered diagnostic procedures in surgery for exclusion or confirmation of fracture. It would be highly beneficial if - as a by-product of conventional imaging - one could obtain a quantitative parameter that is closely correlated with femoral BMD in addition to the original diagnostic information, e.g. fracture status at the peripheral site. Previous studies could demonstrate a correlation between calcaneal BMD and osteoporosis. The objective of our study was to test the hypothesis that topological analysis of calcaneal bone texture depicted by a lateral x-ray projection of the ankle allows to estimate femoral BMD. Our analysis on 34 post-menopausal patients indicate that texture properties based on graylevel topology in calcaneal x-ray-films are closely correlated with BMD at the hip and may qualify as a substitute indicator of femoral fracture risk.

Paper Details

Date Published: 27 March 2009
PDF: 7 pages
Proc. SPIE 7259, Medical Imaging 2009: Image Processing, 725954 (27 March 2009); doi: 10.1117/12.810738
Show Author Affiliations
H. F. Boehm, Ludwig-Maximilians-Univ. Munich (Germany)
J. Lutz, Ludwig-Maximilians-Univ. Munich (Germany)
M. Koerner, Ludwig-Maximilians-Univ. Munich (Germany)
M. Notohamiprodjo, Ludwig-Maximilians-Univ. Munich (Germany)
M. Reiser, Ludwig-Maximilians-Univ. Munich (Germany)

Published in SPIE Proceedings Vol. 7259:
Medical Imaging 2009: Image Processing
Josien P. W. Pluim; Benoit M. Dawant, Editor(s)

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