
Proceedings Paper
Perfusion from angiogram and a priori (PAP) with temporal regularizationFormat | Member Price | Non-Member Price |
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Paper Abstract
Perfusion imaging is often used for diagnosis and for assessment of the response to the treatment. If perfusion can be
measured during interventional procedures, it could lead to quantitative, more efficient and accurate treatment; however,
imaging modalities that allow continuous dynamic scanning are not available in most of procedure rooms. Thus, we
developed a method to measure the perfusion-time attenuation curves (TACs)-of regions-of-interest (ROIs) using xray
C-arm angiography system with no gantry rotation but with a priori. The previous study revealed a problem of large
oscillations in the estimated TACs and the lack of comparison with
CT-based approaches. Thus the purposes of this
study were (1) to reduce the variance of TDCs; and (2) to compare the performance of the improved PAP with that of
the CT-based perfusion method. Our computer simulation study showed that the standard deviation of PAP method was
decreased by 10.7-59.0% and that it outperformed (20× or 200× times) higher dose CT methods in terms of the
accuracy, variance, and the temporal resolution.
Paper Details
Date Published: 14 March 2009
PDF: 7 pages
Proc. SPIE 7258, Medical Imaging 2009: Physics of Medical Imaging, 72582I (14 March 2009); doi: 10.1117/12.810588
Published in SPIE Proceedings Vol. 7258:
Medical Imaging 2009: Physics of Medical Imaging
Ehsan Samei; Jiang Hsieh, Editor(s)
PDF: 7 pages
Proc. SPIE 7258, Medical Imaging 2009: Physics of Medical Imaging, 72582I (14 March 2009); doi: 10.1117/12.810588
Show Author Affiliations
Katsuyuki Taguchi, The Johns Hopkins Univ. School of Medicine (United States)
Jean-Francois H. Geschwind, The Johns Hopkins Univ. School of Medicine (United States)
Published in SPIE Proceedings Vol. 7258:
Medical Imaging 2009: Physics of Medical Imaging
Ehsan Samei; Jiang Hsieh, Editor(s)
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