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Proceedings Paper

Serum protein profile study of clinical samples using high performance liquid chromatography-laser induced fluorescence: case of cervical and oral cancers
Author(s): Gopal Karemore; . Sujatha; Lavanya Rai; Keerthilatha M. Pai; V. B. Kartha; . Santhosh C.
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Paper Abstract

The serum protein profiles of normal subjects, patients diagnosed with cervical cancer, and oral cancer were recorded using High Performance Liquid Chromatography combined with Laser Induced Fluorescence detection (HPLC-LIF). Serum protein profiles of the above three classes were tested for establishing the ability of HPLC-LIF protein profiling technique for discrimination, using hard clustering and Fuzzy clustering methods. The clustering algorithms have quite successfully classified the profiles as belonging to normal, cancer of cervix, and oral cancer conditions.

Paper Details

Date Published: 23 February 2009
PDF: 9 pages
Proc. SPIE 7182, Imaging, Manipulation, and Analysis of Biomolecules, Cells, and Tissues VII, 71820J (23 February 2009); doi: 10.1117/12.809930
Show Author Affiliations
Gopal Karemore, Univ. of Copenhagen (Denmark)
Nordic Bioscience (Denmark)
. Sujatha, Manipal Univ. (India)
Lavanya Rai, Manipal Univ. (India)
Keerthilatha M. Pai, Manipal Univ. (India)
V. B. Kartha, Manipal Univ. (India)
. Santhosh C., Manipal Univ. (India)

Published in SPIE Proceedings Vol. 7182:
Imaging, Manipulation, and Analysis of Biomolecules, Cells, and Tissues VII
Daniel L. Farkas; Dan V. Nicolau; Robert C. Leif, Editor(s)

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