
Proceedings Paper
A pressure controlled low-level laser probe to enhance photon density in soft tissueFormat | Member Price | Non-Member Price |
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Paper Abstract
Noninvasive low-level laser devices have been introduced for therapeutic purpose in medicine. However, low-level laser
cannot deliver enough photon density to expect positive therapeutic results in deep tissue layer due to light scattering
property in tissue. In order to overcome the limitation, this study was aimed to develop a negative pressure applied low-level
laser probe to enhance laser transmission and, therefore, photon density in soft tissue. In order to evaluate clinical
feasibility of developed laser probe, ex-vivo experiments were performed with porcine skin samples and laser
transmissions were quantitatively measured as a function of tissue compression. The laser probe has an air suction hole
to apply negative pressure to skin, a transparent plastic body to observe tissue deformation, and a small metallic optical
fiber guide to support the optical fiber when negative pressure was applied. By applying negative pressure to the laser
probe, the porcine skin under the fiber guide is compressed down and, low-level laser is emitted into the skin. Diffusion
images of laser in the skin samples were acquired with a CCD camera and analyzed. Compared to the intensity without compression, the peak intensity of laser beam profiles increased about 2~2.5 times and FWHM (Full Width at Half Maximum) decreased about 1.67~2.85 times. In addition, the peak intensity was linearly increased as a function of
compression. In conclusion, we verified the enhancement of laser transmission and therefore, photon density in tissue by
applying negative pressure to the developed low-level laser probe and its potential for clinical usefulness.
Paper Details
Date Published: 23 February 2009
PDF: 9 pages
Proc. SPIE 7161, Photonic Therapeutics and Diagnostics V, 71610R (23 February 2009); doi: 10.1117/12.809924
Published in SPIE Proceedings Vol. 7161:
Photonic Therapeutics and Diagnostics V
Henry Hirschberg M.D.; Brian Jet-Fei Wong M.D.; Kenton W. Gregory M.D.; Reza S. Malek; Nikiforos Kollias; Bernard Choi; Guillermo J. Tearney; Justus F. R. Ilgner; Steen J. Madsen; Laura Marcu; Haishan Zeng, Editor(s)
PDF: 9 pages
Proc. SPIE 7161, Photonic Therapeutics and Diagnostics V, 71610R (23 February 2009); doi: 10.1117/12.809924
Show Author Affiliations
Changmin Yeo, Yonsei Univ. (Korea, Republic of)
Taeyoon Son, Yonsei Univ. (Korea, Republic of)
Heesung Kang, Yonsei Univ. (Korea, Republic of)
Junghwan Park, Yonsei Univ. (Korea, Republic of)
Taeyoon Son, Yonsei Univ. (Korea, Republic of)
Heesung Kang, Yonsei Univ. (Korea, Republic of)
Junghwan Park, Yonsei Univ. (Korea, Republic of)
Yong-Heum Lee, Yonsei Univ. (Korea, Republic of)
Kyoung Joung Lee, Yonsei Univ. (Korea, Republic of)
Byungjo Jung, Yonsei Univ. (Korea, Republic of)
Kyoung Joung Lee, Yonsei Univ. (Korea, Republic of)
Byungjo Jung, Yonsei Univ. (Korea, Republic of)
Published in SPIE Proceedings Vol. 7161:
Photonic Therapeutics and Diagnostics V
Henry Hirschberg M.D.; Brian Jet-Fei Wong M.D.; Kenton W. Gregory M.D.; Reza S. Malek; Nikiforos Kollias; Bernard Choi; Guillermo J. Tearney; Justus F. R. Ilgner; Steen J. Madsen; Laura Marcu; Haishan Zeng, Editor(s)
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