Proceedings Paper
Image-guided optical spectroscopy in diagnosis of osteoarthritis by combining spectral and spatial a priori information| Format | Member Price | Non-Member Price |
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Paper Abstract
A multi-modality imaging approach and instrument that integrate optical imaging system and
near-infrared spectroscopy into an x-ray tomosynthesis setup have been employed to perform a
clinical study of image-guided spectroscopy on osteoarthritis (OA) in the finger joints. The multiwavelength
spectroscopy of the joints using x-ray-guided spatial constraints provides 3D images
of oxygen saturation and water content with high resolution and improved quantitative capability.
Based on the recovered quantitative results from 18 healthy volunteers and 22 patients, we
observed that oxygen saturation and water content were significant discriminators for
differentiation of healthy joints from diseased ones. The recovered images appear to show that the
OA joints have high water values and decreased oxygen saturation.
Paper Details
Date Published: 12 February 2009
PDF: 12 pages
Proc. SPIE 7174, Optical Tomography and Spectroscopy of Tissue VIII, 71740K (12 February 2009); doi: 10.1117/12.809556
Published in SPIE Proceedings Vol. 7174:
Optical Tomography and Spectroscopy of Tissue VIII
Bruce J. Tromberg; Arjun G. Yodh; Mamoru Tamura; Eva M. Sevick-Muraca; Robert R. Alfano, Editor(s)
PDF: 12 pages
Proc. SPIE 7174, Optical Tomography and Spectroscopy of Tissue VIII, 71740K (12 February 2009); doi: 10.1117/12.809556
Show Author Affiliations
Zhen Yuan, Univ. of Florida (United States)
Qizhi Zhang, Univ. of Florida (United States)
Huizhu Jiang, Univ. of Florida (United States)
Qizhi Zhang, Univ. of Florida (United States)
Huizhu Jiang, Univ. of Florida (United States)
Published in SPIE Proceedings Vol. 7174:
Optical Tomography and Spectroscopy of Tissue VIII
Bruce J. Tromberg; Arjun G. Yodh; Mamoru Tamura; Eva M. Sevick-Muraca; Robert R. Alfano, Editor(s)
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