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Proceedings Paper

Wide field visualization of retinal and choroidal microstructure in vivo using frequency domain OCT at 1060 nm with up to 47000 lines/s
Author(s): Boris Hermann; M. Esmaeelpour; Boris Povazay; Bernd Hofer; F. Bounaparte; Nick Sheen; Rachel North; Wolfgang Drexler
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Paper Abstract

We present in vivo frequency domain optical coherence tomography of the human retina and choroid in the 1060 nm water transmission window with 72 nm optical bandwidth (<8 &mgr;m axial resolution in tissue) and up to 74 frames per second (`a 512 x 512 pixels). A novel InGaAs stripe array with 1024 pixels and 47000 lines/s read out rate is utilized in combination with an all reflective spectrometer to enable densely sampled wide field scans (35°x°35), i.e. ~­10x10 mm2) acquired in less than 7 seconds. At this speed numerical motion artifact removal algorithms are sufficient to compensate remaining involuntary drifts of the subject's eye. Enhanced penetration beyond the retina enables for the first time highly isotropically sampled, three-dimensional visualization of all three layers of the choroidal vasculature without the need of contrast agents, the choroidal-scleral interface as well as the first scleral layer, the absorbing lamina fusca sclerae. Furthermore the choroidal thickness was quantified in 30 healthy subjects and correlated with axial eye length. First results indicate an decrease in choroidal thickness with increasing axial eye length.

Paper Details

Date Published: 23 February 2009
PDF: 6 pages
Proc. SPIE 7163, Ophthalmic Technologies XIX, 71630A (23 February 2009); doi: 10.1117/12.809253
Show Author Affiliations
Boris Hermann, Cardiff Univ. (United Kingdom)
M. Esmaeelpour, Cardiff Univ. (United Kingdom)
Boris Povazay, Cardiff Univ. (United Kingdom)
Bernd Hofer, Cardiff Univ. (United Kingdom)
F. Bounaparte, Cardiff Univ. (United Kingdom)
Nick Sheen, Cardiff Univ. (United Kingdom)
Rachel North, Cardiff Univ. (United Kingdom)
Wolfgang Drexler, Cardiff Univ. (United Kingdom)

Published in SPIE Proceedings Vol. 7163:
Ophthalmic Technologies XIX
Fabrice Manns; Per G. Söderberg; Arthur Ho, Editor(s)

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