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Proceedings Paper

Three-dimensional photonic devices fabricated by ultrafast lasers for optical sensing in lab-on-a-chip
Author(s): R. Martínez Vázquez; R. Osellame; A. Crespi; C. Dongre; H. J. W. M. Hoekstra; M. Pollnau; H. H. van den Vlekkert; R. van Weeghel; P. Watts; R. Ramponi; G. Cerullo
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Paper Abstract

We report on the use of femtosecond laser pulses to fabricate photonic devices (waveguides and interferometers) inside commercial CE chips without affecting the manufacturing procedure of the microfluidic part of the device. The fabrication of single waveguides intersecting the channels allows one to perform absorption or Laser Induced Fluorescence (LIF) sensing of the molecules separated inside the microchannels. Microfluidic channels, with access holes, are fabricated using femtosecond laser irradiation followed by chemical etching. Mach-Zehnder interferometers are used for label-free sensing of the samples flowing in the microfluidic channels by means of refractive index changes detection.

Paper Details

Date Published: 24 February 2009
PDF: 11 pages
Proc. SPIE 7203, Commercial and Biomedical Applications of Ultrafast Lasers IX, 720313 (24 February 2009); doi: 10.1117/12.809142
Show Author Affiliations
R. Martínez Vázquez, IFN-CNR, Politecnico di Milano (Italy)
R. Osellame, IFN-CNR, Politecnico di Milano (Italy)
A. Crespi, IFN-CNR, Politecnico di Milano (Italy)
C. Dongre, Univ. of Twente (Netherlands)
H. J. W. M. Hoekstra, Univ. of Twente (Netherlands)
M. Pollnau, Univ. of Twente (Netherlands)
H. H. van den Vlekkert, LioniX BV (Netherlands)
R. van Weeghel, LioniX BV (Netherlands)
P. Watts, The Univ. of Hull (United Kingdom)
R. Ramponi, IFN-CNR, Politecnico di Milano (Italy)
G. Cerullo, IFN-CNR, Politecnico di Milano (Italy)

Published in SPIE Proceedings Vol. 7203:
Commercial and Biomedical Applications of Ultrafast Lasers IX
Joseph Neev; Stefan Nolte; Alexander Heisterkamp; Rick P. Trebino, Editor(s)

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