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Proceedings Paper

Flow measurement by using the signal decrease of moving scatterers in spatially encoded Fourier domain optical coherence tomography
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Paper Abstract

Blood flow measurement with spectrometer-based Fourier domain optical coherence tomography (FD-OCT) is limited by the motion-induced signal fading and the resulting reduction of flow sensitivity. Therefore, we have numerically simulated the signal power decrease of an obliquely moved scattering layer as a function of the absolute sample velocity composed of an axial and transverse component. In contrast to the prevalent expectance, the resulting signal damping is not only the sum of axial and transverse effect. In this study, we take advantage of the signal decay and present the feasibility to quantify high flow velocities at which the standard Doppler OCT does not work any longer. For the validation of our approach, a flow phantom model consisting of a 1%-Intralipid solution and a 320 μm glass capillary was used. With this phantom study, depth-resolved flow was visualized and the quantitative velocities were extracted from the OCT images without phase information.

Paper Details

Date Published: 20 February 2009
PDF: 12 pages
Proc. SPIE 7168, Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XIII, 71681S (20 February 2009); doi: 10.1117/12.808737
Show Author Affiliations
Julia Walther, Univ. of Technology Dresden (Germany)
Edmund Koch, Univ. of Technology Dresden (Germany)

Published in SPIE Proceedings Vol. 7168:
Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XIII
James G. Fujimoto; Joseph A. Izatt; Valery V. Tuchin, Editor(s)

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