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Proceedings Paper

OLED-polypropylene bio-CD sensor
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Paper Abstract

With the goal of developing microfluidic platforms for sensing applications, flash-free micro patterns were embossed in polypropylene surfaces with ultrasonic heating for a biosensing lab-on-CD application. The embossed features were designed to act as reservoirs, valves, and reaction chambers to allow, in combination with a compact sensing platform, the monitoring of analyte levels using a standard PC-CD player. To generate the compact sensor, as an example, we chose the photoluminescence (PL)-based detection of lactate and glucose using an OLED-based sensing platform. Once embossed, the surface energy of the plastic substrate was chemically modified to make it hydrophilic. Reagents, placed in separate reservoirs, were directed through burst valves towards a reaction chamber via CD rotation. Lactate or glucose were monitored by measuring the effect of the related dissolved oxygen level on the PL decay time of an oxygen-sensitive dye, following analyte oxidation catalyzed by a suitable specific oxidase enzyme. The results demonstrate the potential of integrating OLEDs as excitation sources in PL-based sensors with microfluidic CD-based platforms, including for simultaneous multiple analyses.

Paper Details

Date Published: 28 August 2008
PDF: 8 pages
Proc. SPIE 7054, Organic Field-Effect Transistors VII and Organic Semiconductors in Sensors and Bioelectronics, 70541H (28 August 2008); doi: 10.1117/12.794231
Show Author Affiliations
Srikanth Vengasandra, Iowa State Univ. (United States)
Yuankun Cai, Ames Lab., Iowa State Univ. (United States)
David Grewell, Iowa State Univ. (United States)
Joseph Shinar, Ames Lab., Iowa State Univ. (United States)
Ruth Shinar, Iowa State Univ. (United States)

Published in SPIE Proceedings Vol. 7054:
Organic Field-Effect Transistors VII and Organic Semiconductors in Sensors and Bioelectronics
Zhenan Bao; Ruth Shinar; Iain McCulloch, Editor(s)

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