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Proceedings Paper

Amperometric immunosensor using electric field to improve the interaction between antibody and antigen
Author(s): Jizhou Sun; Chao Bian; Shanhong Xia
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Paper Abstract

This paper proposes a method that using an electric field to improve the immobilization of analyte in an amperometric immunosensor. The amperometric immunosensor, which has a two-microelectrode system enclosed in a SU-8 reaction microwell, has been developed with MEMS technology for the detection of the human immunoglobulin (HIgG). Electric field has been applied above the working electrode by setting the appropriate potential between two electrodes to enable more antigen "IgG" to be assembled to the sensing interface with less time. The results demonstrate that the immunochemical incubation time spent on the immobilization of HIgG has been shortened, and the property of the immunosensor has been enhanced.

Paper Details

Date Published: 8 January 2008
PDF: 7 pages
Proc. SPIE 6836, MEMS/MOEMS Technologies and Applications III, 68360C (8 January 2008); doi: 10.1117/12.775039
Show Author Affiliations
Jizhou Sun, Institute of Electronics (China)
Chao Bian, Institute of Electronics (China)
Shanhong Xia, Institute of Electronics (China)

Published in SPIE Proceedings Vol. 6836:
MEMS/MOEMS Technologies and Applications III
Jung-Chih Chiao; Xuyuan Chen; Zhaoying Zhou; Xinxin Li, Editor(s)

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